How to Perform Karl Fischer (KF) Moisture Analysis on Complex Samples?
The Karl Fischer method is an analytical method for the determination of moisture proposed by Karl Fischer in 1935. It is suitable for the determination of all kinds of substances: chemicals, oils, pharmaceuticals and food , etc . At present, Karl Fischer titration has developed into a moisture analysis method widely used in the world. In this article, we will discuss how the Karl Fischer moisture detection test can be applied to complex samples. I nsoluble samples In the moisture detection of some samples, laboratory personnel may often encounter that some samples are difficult to dissolve or have poor solubility, resulting in the inability to accurately measure the moisture content of the sample. Usually when encountering insoluble samples, researchers can increase the solubility of the sample by adding a co-solvent, and further measure the water content in the sample. How to select a suitable co-solvent? l No sid...