Alfa Chemistry Starts to Supply Quaternary Phosphonium Compounds for Formulation of Disinfectants and Antiseptics
Earlier this month, the New York-based chemical supplier Alfa Chemistry announces its decision to start to provide quaternary phosphonium compounds ( QPCs ), which proves to be effective antimicrobial scaffolds with improved broad-spectrum activities compared to commercial Quaternary Ammonium Compounds ( QACs ) . A s a key class of organophosphorus compounds, QPCs can be synthesized by routes involving nucleophilic phosphorus. With potent bioactivities, biscationic phosphonium compounds are viewed as the next-generation disinfectant molecules, arousing more future studies into the synthesis and biological investigation of this nascent antimicrobial class. QPCs have gained considerable attention as catalysts in many chemical transformations and synthetic chemistry because of their unique chemical structure. The chemical reactions that QPCs can be used: l Wittig reaction l Reduction reaction l Friedel-Crafts-type reaction l Other reaction s In addition to the...