Alfa Chemistry Blog

Having been involved with the analytical standards industry for years, Alfa Chemistry recently announces earlier this month that certified reference materials for chromatography are now available. Previously, the company has already released a wide range of chromatography standards for laboratory researchers worldwide, including: clinical standards, environmental standards, food & beverage standards, forensic and veterinary standards, life sciences standards, petrochemical standards, pharmaceutical and drug standards and more. Certified reference materials for chromatography, often accompanied by a certificate, are mainly used for purposes like quality assurance, calibration, validation of analytical methods, interlaboratory trials or traceability of results to acknowledged standards. “To ensure the accelerated success of for various research projects, we offer stable and high purity chromatography standards. Also, large package of customized standards can be produced upon cli...

In response to the market trend, the New York-based chemical supplier Alfa Chemistry announces to further optimize its offering of protection reagents by classifying them into a number of smaller groups. After the implementation of this move, visitors to the website of Alfa Chemistry can easily locate the reagents they need by just searching or scanning through different groups, which are: 2-(trimethylsilyl)ethoxycarbonylation (Teoc) reagents, 9-fluorenylmethyloxycarbonylation (Fmoc) reagents, acetalization reagents, acylation reagents, alkoxymethylation reagents, allylation reagents, allyloxycarbonylation (Alloc) reagents, benzylation (Bn) reagents, benzyloxycarbonylation (Cbz) reagents, photolabile protection reagents, silylation reagents, sulfonylation reagents, tert-Butoxycarbonylation (Boc) reagents, thioacetalization reagents , trichloroethoxycarbonylation reagents, tritylation (Tr) reagents as well as other protecting reagents. Organic synthesis is a preferred method to syn...

The compounds conjugated with PEG (functional PEGs) have many advantages. Ever since its discovery, PEGylation is of increasing interest in biological and medical studies owing to their solubility in water, excellent biocompatibility and non-immunogenicity. The US-based chemical supplier Alfa Chemistry announces in a recent statement that it starts to provide functional PEGs for scientific research. Polyethylene glycol (PEG) is a versatile polyether compound being utilized in various areas ranging from industrial manufacturing to medicine. In the process of PEGylation, PEG is bonded to another molecule to accomplish certain goal. Now PEGylation has become an attractive and promising therapeutic method. “The importance of PEG in drug delivery lies in its ability to hinder the protein adsorption and thus minimize the protein corona formation,” says the Marketing Chief of Alfa Chemistry. “In general, PEG can be conjugated to many chemicals such as peptide, low molecular weight drugs,...

In organic synthesis, a molecule may contain two or more functional groups. In order to prevent one of the functional groups from being destroyed by the reaction, a certain reagent is often used to protect it first, and the protective agent will be removed after the reaction is completed. The protection of hydroxyl, amino and amino groups are most commonly seen. There are many types of protective reagents, which are widely used in the synthesis of drug molecules. Each protective reagent has corresponding de-protection conditions. What is protecting group? As mentioned above, the protecting group is a group whose main purpose is to protect the functional group (improve its stability) through a specific chemical reaction. Various protecting groups have been developed to stabilize the chemical properties of the original site according to the purpose. In addition, protecting groups can also bring about many other benefits: Improve solubility and reduce polarity Sugars and amino a...

Due to its biological inertness and good biocompatibility, polyethylene glycol (PEG) has a wide range of applications in the pharmaceutical industry, biological materials, cosmetics, and analytical science. A number of compounds, such as proteins, peptides, oligonucleotides, drugs and liposomes, after being modified by PEG covalent bonding, can effectively extend the circulation time in the body, increase stability, optimize pharmacokinetics and reduce side effects. Functional PEG has huge potentials in different scenarios. According to MarketsandMarkets, the global PEG-modified drug market in 2017 was 10.388 billion U.S. dollars, and is expected to reach 17.813 billion U.S. dollars by 2025, with a significant growth rate. As of the end of 2019, 26 PEGylated drugs have been approved by the FDA or the European Union. Except for 2 small molecule drugs and 1 liposome drug, the remaining 23 are all PEGylated protein/peptide drugs. On the whole, PEGylation can be used for PEGylated pro...

Graphene has been established as one of the most influential materials on earth and its discovery won the Nobel Prize in Physics in 2010. Having a wealth of expert knowledge in the field of graphene, Alfa Chemistry today announces the launch of a diversified graphene series for researchers from both scientific and industrial communities. Previously the company has already released a rich collection of graphene-related products and solutions. Graphene is the thinnest, strongest and lightest material yet with incredible strength and elasticity. “The past decade witnessed the huge prospects of graphene in materials science, energy, and biomedicine. Their excellent optical, electrical, and mechanical properties have brought infinite possibilities. For example, graphene helps many electronic products and batteries to achieve better performance,” says the Marketing Chief of Alfa Chemistry. Considering the popularity of graphene among companies and research laboratories around the world,...

Semiconductors are changing the World now. Considering the growing needs for semiconductors worldwide, Alfa Chemistry’s management decides to launch a completely new website for the showcase of its broad portfolio of advanced high-purity semiconductor chemicals and materials. All these products are suitable for semiconductor research in optics, MEMS and solar energy industries. “We offer a wide selection of semiconductor chemicals and materials for global manufacturers, and the semiconductor products they made are closely related to our daily life and will power our digital world,” commented the Marketing Chief of Alfa Chemistry. The products provided by Alfa Chemistry Semiconductor cover the following: Semiconductor chemical products , which further include: high-quality silicon wafer (damp heat oxide, dry heat oxide, dry chlorinated thermal oxide), photolithography (photolithographic monomer, photoresist, nano-printing lithography and micro-contact printing stamps), high purit...

Alfa Chemistry recently announces to offer a comprehensive range of halide quaternary ammonium salts , which is just one type of its diversified offering of quaternary ammonium compounds (QACs), covering acid radical quaternary ammonium salts, polyquaternium, quaternary ammonium hydroxide, and quaternary phosphonium compounds. Halide quaternary ammonium salts are the most commonly seen quaternary ammonium salts, and are widely used in sterilizing scenarios. “We offer various halide quaternary ammonium salts. Till now, fluoride series, chloride series, bromide series and iodide series can be easily obtained at our company. Customers can search the CAS No. or just put in the chemical name they are interested in the search bar of our website,” says the Marketing Chief of Alfa Chemistry. Fluoride Series The fluoride series of halide quaternary ammonium salts that Alfa Chemistry offers include: Benzyltrimethylammonium fluoride hydrate (CAS 127582-36-9), Hexadecyl trimethyl ammonium fl...

The past decade has seen microfluidics as a distinct new area of research, which found widespread applications in chemistry, biology, medicine, physical sciences as well as many other fields. Being an active player in the biotechnology industry, Alfa Chemistry recently launches a sub-website specially focusing on microfluidics research. The products and services provided are aiming to transform clients’ amazing microfluidics ideas into reality. Microfluidics is the technology to manipulate fluids in channels with dimensions of tens of micrometres, which has the potential to influence areas from chemical synthesis and biological analysis to optics and information technology. To help address challenges arising from the process of conducting microfluidics research, Alfa Chemistry’s microfluidics R&D team fully taps imagination and ingenuity and spares no effort to develop new, first-class fluid products and services to meet the industry demands, offering effective yet feasible sol...